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Updated:Apr 23, 2026
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The Black Death's spread along Silk Road routes (1346–1353 CE)

The Black Death's spread along Silk Road routes (1346–1353 CE)

  1. Silk Road connectivity links distant disease reservoirs

    Labels: Silk Road, Caravanserai
  2. Plague outbreak reported in Black Sea steppe zone

    Labels: Black Sea, Italian merchant
  3. Genoese ships carry plague west from Kaffa

    Labels: Genoese ships, Mediterranean shipping
  4. Plague reaches Constantinople via Black Sea shipping

    Labels: Constantinople, Emperor John
  5. Messina outbreak marks entry into western Mediterranean

    Labels: Messina, Sicily
  6. Genoa and Venice become major distribution nodes

    Labels: Genoa, Venice
  7. North Africa and western European coasts affected

    Labels: North Africa, Western Europe
  8. Plague crosses the English Channel to southern England

    Labels: Melcombe Regis, English Channel
  9. London experiences peak mortality in early 1349

    Labels: London, Urban mortality
  10. Central and northern Europe drawn into the epidemic

    Labels: Central Europe, Baltic region
  11. First Black Death wave subsides across Eurasian routes

    Labels: First wave, Quarantine origins